Homophilic Interaction of Junctional Adhesion Molecule
نویسندگان
چکیده
منابع مشابه
Hematopoietic / Endothelial Homophilic Adhesion Molecule
http://bloodjournal.hematologylibrary.org/content/92/12/4602.full.html Updated information and services can be found at: (3094 articles) Hematopoiesis and Stem Cells Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety ma...
متن کاملIntercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion
Intercellular adhesion molecule-5 (ICAM-5) is a dendritically polarized membrane glycoprotein in telencephalic neurons, which shows heterophilic binding to leukocyte beta(2)-integrins. Here, we show that the human ICAM-5 protein interacts in a homophilic manner through the binding of the immunoglobulin domain 1 to domains 4-5. Surface coated ICAM-5-Fc promoted dendritic outgrowth and arborizati...
متن کاملCryo-electron tomography of homophilic adhesion mediated by the neural cell adhesion molecule L1.
The neural cell adhesion molecule L1 participates in homophilic interactions important for axon guidance and neuronal development. The structural details of homophilic adhesion mediated by L1 and other immunoglobulin superfamily members containing an N-terminal horseshoe arrangement of four immunoglobulin-like domains are unknown. Here we used cryo-electron tomography to study liposomes to whic...
متن کاملSingle-molecule force spectroscopy of the Aplysia cell adhesion molecule reveals two homophilic bonds.
Aplysia californica neurons comprise a powerful model system for quantitative analysis of cellular and biophysical properties that are essential for neuronal development and function. The Aplysia cell adhesion molecule (apCAM), a member of the immunoglobulin superfamily of cell adhesion molecules, is present in the growth cone plasma membrane and involved in neurite growth, synapse formation, a...
متن کاملTargeting of junctional adhesion molecule-C inhibits experimental choroidal neovascularization.
PURPOSE To identify the expression of junctional adhesion molecule-C (JAM-C) in choroidal neovascularization (CNV) and evaluate the effect of JAM-C targeting on CNV formation and on cellular functions relevant to CNV in vitro, such as macrophage transmigration, human retinal pigment epithelial (hRPE) cell migration, and monolayer RPE permeability. METHODS JAM-C expression in CNV was analyzed ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2000
ISSN: 0021-9258
DOI: 10.1074/jbc.m003946200